01 Октябрь,2003 | Российская конференция «Аффективные и шизоаффективные расстройства» совместно с Совещанием главных психиатров и руководителей психиатрических учреждений, а также Пленумом Правления Российского общества психиатров
РОССИЙСКАЯ ФЕДЕРАЦИЯ МИНИСТЕРСТВО ЗДРАВООХРАНЕНИЯ МОСКОВСКИЙ НАУЧНО-ИССЛЕДОВАТЕЛЬСКИЙ ИНСТИТУТ ПСИХИАТРИИ
1-3 октября 2003 г. прошла Российская конференция «Аффективные и шизоаффективные расстройства» совместно с Совещанием главных психиатров и руководителей психиатрических учреждений, а также Пленумом Правления Российского общества психиатров.
Основные вопросы для обсуждения на совещании главных специалистов совместно с пленумом Правления РОП.
Предлагаем направлять тезисы докладов на конференции.
Правила оформления тезисов: размер - 1 машинописная страница (1,5 интервала, 14 шрифт), ФИО автора(ов) заглавными буквами, цитирование в тексте без списка литературы.
Оргкомитет рекомендует однократное участие первого автора в направляемых тезисах.
Срок принятия тезисов до 1 июня 2003 г.
Тезисы просим присылать по электронной почте:email@example.com либо firstname.lastname@example.org или по адресу оргкомитета: Москва 107076, Потешная, 3 Московский НИИ психиатрии МЗ РФ (напечатанный текст + электронная версия).
25 Сентябрь,2003 | Serotonin receptor gene haplotype may reduce schizophrenia risk in Japanese carriers - Mental Health
A serotonin receptor gene haplotype may be associated with a reduced risk of schizophrenia in Japanese individuals. Pain & Central Nervous System Week via NewsEdge Corporation : A serotonin receptor gene haplotype may be associated with a reduced risk of schizophrenia in Japanese individuals. "The serotonin 5-HT4 receptor (5-HT4) is implicated in cognitive function, of which impairment is hypothesized as one of the core disturbances of schizophrenia," scientists in Japan noted. "Linkage analysis shows that 5q33.2," which contains the 5-HT4 gene (HTR4), "is a schizophrenia-susceptibility locus." T. Suzuki and colleagues at Fujita Health University hypothesized that variation in HTR4 "modifies genetic susceptibility to schizophrenia." In their study, "HTR4 coding regions and introns that include the branch sites of HTR4 were investigated in 96 unrelated Japanese schizophrenics using denaturing high-performance liquid chromatography analysis." "One silent single nucleotide polymorphism (SNP) within the coding region and six intronic SNPs were detected," with the 353 + 6G>A mutation "located in a branch site that could effect RNA splicing," they reported. "None of the four SNPs, in which rare-allele frequencies were more than 10% was associated with 189 schizophrenics, in comparison to 299 controls," study data showed. "However, a highly significant association between schizophrenia and haplotype A-T (OR=0.13 [0.03-0.58]) was detected." "These findings suggest that haplotype A-T itself may inhibit the occurrence of schizophrenia, or that another susceptible genetic variants may exist within linkage disequilibrium," the researchers concluded. Suzuki and coauthors published their study in the American Journal of Medical Genetics Part B - Neuropsychiatric Genetics (Association of a haplotype in the serotonin 5-HT4 receptor gene (HTR4) with Japanese schizophrenia. Am J Med Genet Part B, 2003;121B(1):7-13). Additional information can be obtained by contacting N. Iwata, Fujita Health University, School of Medicine, Department of Psychiatry, Toyoake, Aichi 4701192, Japan. The publisher of the American Journal of Medical Genetics Part B - Neuropsychiatric Genetics can be contacted at: Wiley-Liss, Division John Wiley & Sons Inc., 605 Third Avenue, New York, NY 10158-0012, USA. The information in this article comes under the major subject areas of Genomics & Genetics, Mental Health, Neuroscience and Receptor Studies. This article was prepared by Pain & Central Nervous System Week editors from staff and other reports. <> << Copyright ©2003 NewsRx.com >>
15 Сентябрь,2003 | В раздел болезнь и творчество - добавлено 19 статей
В раздел болезнь и творчество - добавлено 19 статей (А.Л. Гройсман, B.C. Ротенберг, Л.С. Выготский, П.Л Капица, М.Г. Ярошевский и др.)
12 Сентябрь,2003 | Психопатические типы в "Братьях Карамазовых". - Д.А. Аменицкий О задачах патографической работы. - П.М. Зиновьев
Психопатические типы в "Братьях Карамазовых". - Д.А. Аменицкий
О задачах патографической работы. - П.М. Зиновьев
10 Сентябрь,2003 | Аффективность, внушение, паранойя - Э. Блейлер
Аффективность, внушение, паранойя - Э. Блейлер
04 Сентябрь,2003 | RNA editing of serotonin 2C receptor may play role in depressive disorders - Mental Health
RNA editing of the serotonin 2C receptor may play a role in the development of depressive disorders. Pain & Central Nervous System Week via NewsEdge Corporation : RNA editing of the serotonin 2C receptor (HTR2C) may play a role in the development of depressive disorders. The importance of HTR2C "in mental disorders has been implicated by studies of HTR2C-deficient mice and linkage and association studies," scientists in Japan explained. "Recent studies have revealed that RNA editing of HTR2C is involved in mental disorders." K. Iwamoto and colleagues at the Institute of Physical and Chemical Research (RIKEN) "examined RNA editing efficiencies of site A and D of HTR2C in the prefrontal cortex samples of patients with bipolar disorder, schizophrenia, and major depression as well as control subjects by using primer extension combined with denaturing high performance liquid chromatography." "We could not find significant alterations of RNA editing efficiencies of these sites in patients," they reported. "However, we found trends for increased RNA editing efficiencies of site D in depressive patients (p=0.08) and site A in suicide victims (p=0.07)." "These findings are in accordance with the previous findings, and suggest that altered RNA editing of HTR2C may have some significance in major depression and suicide," they concluded. Iwamoto and coauthors published their study in Neuroscience Letters (RNA editing of serotonin 2C receptor in human postmortem brains of major mental disorders. Neurosci Lett, 2003;346(3):169-172). For additional information, contact T. Kato, RIKEN, Laboratory for Molecular Dynamics of Mental Disorders, Brain Science Institute, 2-1 Hirosawa, Wako, Saitama 3510198, Japan. The publisher's contact information for the journal Neuroscience Letters is: Elsevier Science Ireland Ltd., Customer Relations Manager, Bay 15, Shannon Industrial Estate, Co. Clare, Ireland. The information in this article comes under the major subject areas of Mental Health, Neuroscience and RNA Research. This article was prepared by Pain & Central Nervous System Week editors from staff and other reports. <> << Copyright ©2003 NewsRx.com >>
04 Сентябрь,2003 | Schizophrenia, manic depression have common genetic cause/ study
PARIS, Sept 5 - Schizophrenia and manic depression have a similar genetic source linked to flawed development of a key component of the central nervous system, a study published in Saturday's Lancet suggests. AFP English Wire via NewsEdge Corporation : PARIS, Sept 5 (AFP) - Schizophrenia and manic depression have a similar genetic source linked to flawed development of a key component of the central nervous system, a study published in Saturday's Lancet suggests. It points the finger at genes that are responsible for myelin, a fatty protein that, like insulation in electrical wiring, coats the strands of nerve cells which send signals to and from the brain. Evidence comes from an assessment of myelin proteins taken from the preserved brains of 15 people who had had schizophrenia; 15 with bipolar disorder, as manic depression is formally known; and 15 individuals who had neither ailment. Schizophrenia and manic depression are major psychotic illnesses that affected roughly one person in 50. Previous avenues of research have explored the theory that the problems lie in brain cells (neurons) themselves; in the gap between those cells, called the synapse; or in chemicals called neurotransmitters which transmit messages between neurons. The study was led by Dmitri Tkachev, a neurobiologist at the Babraham Institute in Cambridge, England. ri/rl Health-disease-schizophrenia AFP 042301 GMT 09 03 <> << Copyright ©2003 Agence France-Presse >>
04 Сентябрь,2003 | Living in Canada can be depressing/ government report
OTTAWA, June 4 - For ten years, the United Nations has been reporting that Canada is one of the best, if not the best, countries to live in. AFP English Wire via NewsEdge Corporation : OTTAWA, June 4 (AFP) - For ten years, the United Nations has been reporting that Canada is one of the best, if not the best, countries to live in. But Canadians have different thoughts according to a just-released government report showing that many find life here depressing. Statistics Canada found that last year "as many Canadians suffer from major depression as from other leading chronic conditions, including heart disease, diabetes or a thyroid condition, according to new data on mental health and well-being from the Canadian Community Health Survey (CCHS)." The government agency said it found that some four percent of those interviewed in the survey reported having experienced symptoms or feelings associated with major depression, compared with five percent with diabetes, five percent with heart disease and six percent with a thyroid condition. Statistics Canada said its survey did not include all mental health disorders, of the five that were dealt with "major depression" led the way with 1,120,000 Canadians suffering from it. Other leading mental health disorders included "mania disorder, panic disorder, social phobia ... as well as alcohol and illicit drug dependence." Statistics Canada said it collected the data between May and December last year from about 37,000 individuals, aged 15 and older. Overall, the survey found, one out of every 10 Canadians, or about 2.6 million people, reported symptoms consistent with alcohol or illicit drug dependence, or one of the five mental disorders covered in the survey, at some time during the 12 months prior to the interview. Men and women appear to show little difference in the proportion of suffering, with about 1.4 million women, or 11 percent of the total, experienced such depression symptoms, compared with 1.2 million men, or 10 percent. hfw/sba/mac Canada-health AFP 041743 GMT 09 03 <> << Copyright ©2003 Agence France-Presse >>
04 Сентябрь,2003 | According to HeartMath Study, Millions Gripped by NEDS - New Study Findings Link Heavy Internet Usage, Information Overload and Social Isolation t
BOULDER CREEK, Calif., Sept. 4 /PRNewswire/ -- Tim Sanders and HeartMath are releasing new findings of a national study that links depression and symptoms of depression with the always-on-economy. The project spokesperson and founder is Tim Sanders, Internet executive and author of the New York Times Bestseller LOVE IS THE KILLER APP. PR Newswire via NewsEdge Corporation : BOULDER CREEK, Calif., Sept. 4 /PRNewswire/ -- Tim Sanders and HeartMath(r) are releasing new findings of a national study that links depression and symptoms of depression with the always-on-economy. The project spokesperson and founder is Tim Sanders, Internet executive and author of the New York Times Bestseller LOVE IS THE KILLER APP. Tim worked at the core of the new economy during its birth and wrote a book about how to survive and thrive during this time of technical efficiency and inhumanity. "In a world of constant interruption and too much information, Love is the Killer App. In short, the solution is not to turn off your computer, but to build your resiliency through warm living," says Sanders. Tim believes technology is good for many things and says it's here to stay but warns that the isolation often created by technology can be devastating. Over the last two years, as he traveled the globe giving keynote speeches and presentations he heard an alarming number of stories from people who are struggling with what he has coined, NEDS -- New Economy Depression Syndrome. NEDS is a self-reinforcing depression brought on by information overload and frequent interruption leading to an erosion of close personal relationships. Symptoms of NEDS include anxiety, exhaustion, burn-out, difficulty making decisions, irritability, sadness, and sleep disturbances. Tim believed underlying many of these symptoms is information overload. For example information workers scan hundreds of pages of information daily while enduring a constant flow of interruptions from cell phones, blackberries, instant messaging and pagers. At the same time, many people lack quality interaction in relationships. Some of us even email the person in the cubicle next to us instead of walking five feet to ask a question. There are also countless others whose primary communications and contact occurs in cyberspace. This combination of information overload, constant interruption and social isolation can be emotionally and physically devastating. Tim realized work had to be more personal. Life in Cyberspace is missing the warmhearted connections that come from more intimate contact -- meeting with people in person, talking live on the phone. "As I traveled the world sharing my theory," he says, "I began to get inundated with emails from people saying that their lives were empty because they lived only in cyberspace -- a cold place. Research from around the world suggested the existence of internet addiction and technology related depression." Based on the Japanese research by Chiba University, combined with the domestic user research by Metafacts, Tim has estimated that over 8 million Americans qualify as NEDS victims. The health effects include heart disease, high blood pressure and reduced immune system performance. The impact on business includes lost productivity. A recent study by the Journal of the American Medical Association estimates that 44 billion dollars are lost each year in productivity because of work related depression -- NEDS could cause a large segment of that loss. This motivated Sanders to create this research project to confirm the relationship between technology use and depression. To validate his theory on NEDS and to help find solutions, Tim teamed with researchers at HeartMath to create and analyze a study aimed at uncovering the symptoms linked to NEDS and to confirm the NEDS hypothesis. The survey was completed in early August 2003. HeartMath is best known for their cutting-edge research and scientifically validated solutions to stress. (http://www.heartmath.com) For over a decade, their research has helped to define the role of the heart in connection to our emotional experiences and how this relationship affects our health, quality of life, cognitive function, and performance. Over 1,500 people participated in the survey testing the NEDS theory. The study, based on survey data from the general population was designed to test the significance of the relationship between PC and internet usage, information overload and depression. The results were controlled for recent stressful life events such as major changes in business and, or personal life. Following are some of the survey findings: * There is a significant relationship between symptoms of depression and the experience of information overload and the number of hours using the Internet. * The more the hours spent on the Internet, the higher the symptoms of depression. * Of those who reported more than 30 hours of weekly Internet usage, 45% feel exhausted often or most of the time and 37% reported having sleep related problems. * Of those who reported more than 30 hours in weekly Internet use, 17% feel less connected with friends and family than they did a year ago. * Those who experienced high levels of information overload also reported increased symptoms of depression. * Of those who reported feeling information overload three or more times per week, 41% feel tense and 43% have difficulty remembering things often or most of the time. * Of those who reported being interrupted by digital devices more than ten times per day, 41% feel exhausted often or most of the time. * Measuring symptoms of depression and information overload, 6.3% of the respondents are candidates for New Economy Depression Syndrome. * Candidates for NEDS were more likely to be male than female. 7.7% of the male participants in the survey were candidates for NEDS, versus 5.6% of the women. * Those who felt warmhearted, and easy-going more often, reported less depression symptoms. These findings were not surprising to HeartMath. HeartMath trains thousands of people each year in major corporations on how to increase workplace performance and reduce stress. HeartMath's work has been published in journals such as the American Journal of Cardiology, Stress Medicine, and Preventive Cardiology. Their POQA survey data of over 4,600 working professionals represents the current workforce and documents a growing trend in stress related issues and symptoms of depression. Of the 4,600 people surveyed by HeartMath as part of their pre-training process, 32% reported feeling exhausted and fatigued often or most of the time and 29% reported feeling anxious often or most of the time. Says Tim, "HeartMath has completed over a decade of research on the subject and has developed a powerful system for helping people deal with anxiety, stress, and feelings of overwhelm. Their training programs emphasis the intelligence of being warmhearted. HeartMath has relevant research that can provide scientifically validated solutions for NEDS. When I wrote my book, LOVE IS THE KILLER APP, I advocated my own personal system that included building powerful and warm relationships with knowledge sharing, networking, and acts of compassion. This system helped me and many others overcome the general level of unhappiness which I now know was NEDS. I needed the warm compassion of others to overcome this. HeartMath's research and solutions support my theory." Terry Real, a leading expert on the subject of depression, and founder of the Relational Recovery Institute, approached Sanders about his findings and offered to contribute valuable thinking based on his clinical experience and knowledge on depression. Real was the first person to discuss male depression in his New York Times best-selling book, I DON'T WANT TO TALK ABOUT IT. Terry Real has been involved in screening respondents to the recent NEDS survey to identify personal stories from people that have recovered or suffered damage to their job, family, health and/or mental well being as a result of NEDS. Terry reflects, "One of our respondents was a doctor with a clear case of NEDS. Her hospital changed to computer-based records. That sounded great on paper, but now instead of talking to a specialist whenever she had a question, she needed to sift through hundred of pages of written materials -- far more than she could possibly digest. She lost her relationships, her sense of creativity and slammed into information overload. The result was a clinical depression." These personal stories may be available as content for an extended show or segment on NEDS. As a therapist Real is particularly impressed with the role of relationships in the NEDS equation. According to Real, "Rich relationships buffer us from the stress of information overload. I am just beginning to look at the solutions, but the direction is clear: High Tech Plus Low Relationships = NEDS. We need to reverse that, encouraging tech-free zones in our workspace and nurturing human interaction." Real sees "Internet Addiction" as part of the larger NEDS picture. He observes, "Addiction is the most extreme form of the process affecting all of us. Technology is seductive, it's fast and easy -- a psychological junk food. The more we turn to it the less satisfied we feel. Then we go back to our emails and cell-phones for another "hit." As a society I think we need to learn how to unplug and hug. You will be more productive, and a lot happier, in the long run." Tim Sanders, Bruce Cryer, President and CEO of HeartMath and depression expert, Terrence Real will be available for national broadcast, print and radio segments and tapings. For More Information and to get advanced information on the complete survey, NEDS and/or any of the partners please contact: Heidi Krupp Krupp Kommunications 212/579-2010 HKrupp KruppKommunications.com or www.kruppkommunications.com or Gabriella Boehmer HeartMath 831-338-8710 gboehmer heartmath.com or go to www.gotneds.com . SOURCE HeartMath -0- 09/04/2003 /CONTACT: Heidi Krupp of Krupp Kommunications, +1-212-579-2010, HKrupp KruppKommunications.com, for HeartMath; or Gabriella Boehmer of HeartMath, +1-831-338-8710, gboehmer heartmath.com / /Web site: http://www.gotneds.com http://www.heartmath.com / CO: HeartMath ST: California IN: CPR HEA PUB BKS MLM SU: SVY KB -- NYTH143 -- 7659 09/04/2003 16:00 EDT http://www.prnewswire.com <> << Copyright ©2003 PR Newswire >>
28 Август,2003 | Illness could cause patients to forget their medication - Schizophrenia
Patients with schizophrenia must take medication regularly to reduce their risk of relapse. But the disease impairs memory, according to new research, meaning these patients may have difficulty in remembering to take their tablets. Medical Letter on the CDC & FDA via NewsEdge Corporation : Patients with schizophrenia must take medication regularly to reduce their risk of relapse. But the disease impairs memory, according to new research, meaning these patients may have difficulty in remembering to take their tablets. Habitual tasks, like taking medicine every few hours, rely on "prospective memory". This type of memory, which appears to be impaired by schizophrenia, enables you to remember that you have to do something in the future, without being prompted. Brita Elvevag, from the Clinical Brain Disorders Branch of the U.S. National Institute of Mental Health and her colleagues who carried out the research published in BMC Psychiatry, wrote, "To our knowledge this is the first study to show that schizophrenia is associated with an overall impairment in habitual prospective memory performance". The authors hypothesized that patients with schizophrenia would have problems with tasks requiring prospective memory. They might mistake remembering they have to do something with remembering they've actually done it. Their hypothesis stemmed from the theory that people with schizophrenia confuse real and imagined events. To test their hypothesis the researchers, based at NIMH and the University of Warwick, compared the prospective memory of people with and without the disease. In each test participants maneuvered a ball around an obstacle course for 90 seconds. They were asked to turn over a counter when they were at least 25 seconds into the test. The time delay ensured that prospective memory had to be used. Participants with schizophrenia were more likely to forget to turn over the counter. At the end of the test the participants were asked if they had remembered to turn over the counter. Approximately a third of the time participants with schizophrenia reported they had done so when they had not. Elvevag and colleagues wrote, "This would seem a worryingly high probability for such an apparently simple task that posed few problems for control participants. ... Our result suggests that patients' self-reports of having completed a habitual prospective memory task, for example taking medication, are likely to be particularly unreliable". Schizophrenia affects one in every hundred people at some point during their lives. While there is no cure, it is treatable with antipsychotic drugs. About 80% of those patients who stop taking their medications after an acute episode of schizophrenia will have a relapse within a year (Elvevag B, Maylor EA, Gilbert AL. Habitual prospective memory in schizophrenia. BMC Psychiatry, 2003;3:9). This article was prepared by Medical Letter on the CDC & FDA editors from staff and other reports. <> << Copyright ©2003 NewsRx.com >>
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