05 Ноябрь, 2002
Early treatment of schizophrenia with atypical antipsychotics may improve outcome
Cannon TD, Huttunen MO, Dahlstr?m M et al. Antipsychotic drug treatment in the prodromal phase of schizophrenia. Am J Psychiatry 2002:159:1230 - 2. Early drug treatment gives a better long-term outcome for patients with schizophrenia, possibly because it slows deterioration. This Finnish, multicentre, open-label trial showed that starting a low-dose atypical antipsychotic (risperidone) early improved thought and behaviour disturbances in prodromal and first-episode patients. Four prodromal high-risk adolescents (15 - 20 years) and six first-episode patients (16 - 35 years) were treated with average doses of 1.0 and 1.8mg/day respectively, for up to 12 weeks. The maximum daily dose was 2mg/day and 4mg/day for prodromal and first-episode patients, respectively, although this could be titrated downwards. Neurocognitive measures and symptom ratings were taken at baseline and two follow-ups. They were assessed by the California Verbal Learning Test (CVLT; all subject) the Child Behaviour Checklist (CBC; prodromal) and the Positive and Negative Syndrome Scale (PANSS; first episode). On average, both groups significantly improved on the CVLT, and on their respective symptom measures (CBC and PANSS). There were minor adverse events (tremor/tic, exhaustion/anxiety, sedation, dystonia, dry mouth/rhinitis) in five subjects, but these resolved. This study was limited by the small group size, the lack of a placebo control group, and failure to control for practice effects on the neurocognitive tests. Nevertheless, all patients had consistent, statistically significant improvements. The authors concluded it was worth doing a more thorough clinical trial.
04 Ноябрь, 2002
Шизофрения.Ру

вновь заработал сайт www.schizophrenia.ru

02 Ноябрь, 2002
Конференция

02-04.10.2002 в Московском НИИ Психиатрии МЗ РФ прошла конференция "Социальные и клинические проблемы сексологии и сексопатологии".

04 Сентябрь, 2002
Шизофрения.Ру

Приносим пользователям огромные извинения за проблемы на наших серверах с 30.07.02 по 12.08.02. До сих пор не работает домен schizophrenia.ru, сайт можно посмотреть пока здесь, проблема будет устранена в ближайшее время. Открыт раздел "Болезнь и творчество"

04 Июль, 2002
Нервная анорексия - Коркина М. В., Цивилько М. А., Марилов В. В.

Нервная анорексия - Коркина М. В., Цивилько М. А., Марилов В. В.

02 Июль, 2002
Добавлены книги
24 Июнь, 2002
Добавлены книги
18 Июнь, 2002
Добавлены книги
13 Июнь, 2002
Добавлены книги
22 Май, 2002
Юбилей

Научному Центру психического здоровья - 20 лет! Приглашаем принять участие в работе научной конференции, посвященной юбилею НЦПЗ РАМН.