19 Август, 2003
Любовь у помешанных - Чезаре Ломброзо

Любовь у помешанных - Чезаре Ломброзо

28 Июль, 2003
Клинический архив гениальности и одаренности - 1925 год выпуск 1
28 Июль, 2003
Клинический архив гениальности и одаренности - 1925 год выпуск 2
22 Июль, 2003
Психиатрические эскизы из истории, Том II - П. И. Ковалевский.
21 Июль, 2003
Daughters of older fathers at increased schizophrenia risk
LONDON Newswire reporters Children born when their fathers are 50 or older are at increased risk of developing schizophrenia, according to Danish and US researchers.And the risk may be slightly higher in girls than in boys, suggesting that a new mutation on the X chromosome might be the cause of some cases of schizophrenia. HMG - Health Newswire Professional via NewsEdge Corporation : LONDON By Health Newswire reporters Children born when their fathers are 50 or older are at increased risk of developing schizophrenia, according to Danish and US researchers.And the risk may be slightly higher in girls than in boys, suggesting that a new mutation on the X chromosome might be the cause of some cases of schizophrenia. Previous studies have suggested that advanced parental age could be a risk factor for schizophrenia. However, most of these studies did not control for other risk factors, such as death of a parent, family psychiatric history, or socio-economic factors. To address this, Dr Majella Byrne, of Aarhus University in Denmark, and colleagues conducted a case control study which compared 7,704 patients with schizophrenia with 192,590 time-, age-, and sex-matched controls, together with their siblings and parents. All participants were identified using a number of Danish national databases. Because every person born in Denmark is given a unique personal identification number at birth, which is used in all national registers, including health records, the researchers were able to access details on parents and siblings of schizophrenia patients, together with family psychiatric histories. As expected, the researchers found that increasing parental age was associated with an increased risk of schizophrenia in their children. However, after allowing for the fact that older mothers tend to be married to older fathers, only paternal age emerged as a significant risk factor. And after allowing for other known risk factors for schizophrenia, particularly a history of mental illness in either parent, the researchers found that men born when their father was aged 55 or more were at double the risk of developing schizophrenia. In women, however, the relationship was even stronger. The team found that women born to fathers aged 50 or over were more than twice as likely to develop schizophrenia. This increased to a nearly fourfold risk in those born to fathers aged 55 or more. Reference: Byrne et al, Archives of General Psychiatry 2003;60:673-678 HMG Worldwide 2003 http://www.health-news.co.uk/ Publication: HMG - Health Newswire Professional Distributed by Financial Times Information Limited <> << Copyright ©2003 Financial Times Limited, All Rights Reserved >>
21 Июль, 2003
Rutgers receives $22.6 million to investigate genetics of mental disorders - Research Funding
Rutgers, the State University of New Jersey, has been awarded a $22.6 million, 5-year grant by the U.S. Genomics & Genetics Weekly via NewsEdge Corporation : Rutgers, the State University of New Jersey, has been awarded a $22.6 million, 5-year grant by the U.S. National Institute of Mental Health (NIMH) to establish the Center for Collaborative Genetic Studies on Mental Disorders. The award is the result of a national competition lasting 8 months and involving several levels of review by scientists throughout the United States. The center will be engaged in efforts to discover the genetic bases of mental disorders, such as autism, schizophrenia, bipolar disease and depression. Its scientists also will investigate the genetics of responses to drug therapies for these disorders. The goals of the center are to identify inherited factors that determine individual likelihood for developing each disorder and to establish whether certain groups could be helped by medications tailored to their genetic makeup. This will involve university research and clinical studies in concert with the pharmaceutical industry. "This award reflects the great strides already made by Rutgers scientists and their colleagues in this area of research," said Rutgers President Richard L. McCormick. "We applaud their accomplishments and share with them in the belief that much more can be done to understand and combat these disorders that affect so many individuals and their families." Principal investigator for the center project is Jay Tischfield, Duncan and Nancy MacMillan Professor of Genetics and chair of the department of genetics at Rutgers, and professor of pediatrics and psychiatry, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey. "A decisive factor in this award was the Rutgers University Cell and DNA Repository (RUCDR), a world-renowned facility that supports research on the genetics of complex human diseases," said Tischfield. Established in 1998 on Rutgers' Busch campus, the RUCDR supports National Institutes of Health and privately funded charitable research on mental diseases; disorders such as heroin, cocaine and tobacco abuse; diabetes and obesity; and aging and longevity. "The center will play a critical role in future genetic studies on mental disorders in the postgenomic era," said Steven Moldin, NIMH project director for the center. "Rutgers has assembled a world-class research team with cutting-edge scientific expertise, and the center will foster collaborations, produce critical resources, and implement state-of-the-art methods to characterize the genetic basis of mental disorders. We expect that the center's activities will greatly accelerate the identification of disease-vulnerability genes and the development of new drug therapies," said Moldin, who is also director of the Office of Human Genetics and Genomic Resources and associate director of the Division of Neuroscience and Basic Behavioral Science at NIMH. The NIMH award includes a $2.1 million subcontract to Professor John Rice and colleagues at the Washington University School of Medicine, St. Louis. Rice and Tischfield will serve as center codirectors. In addition, Rutgers' genetics faculty members Linda Brzustowicz, Steven Buyske, Douglas Fugman, Tara Matise, Amrik Sahota and David Toke are coinvestigators on the project. "Rutgers has played a key role in the recent progress made in identifying genes that determine an individual's risk for specific mental diseases," said Tischfield. "To take this research to the next stage of development will likely require the collaboration of many scientists and clinicians throughout the world." Center scientists will utilize their analytical and technical expertise to allow researchers worldwide to cooperate and share DNA and cell lines produced at Rutgers, as well as clinical and genetic data from thousands of individuals suffering from mental disorders. This article was prepared by Genomics & Genetics Weekly editors from staff and other reports. <> << Copyright ©2003 NewsRx.com >>
16 Июль, 2003
Диссертации:
14 Июль, 2003
Quarter of Australian teens depressed
BRISBANE, July 14 AAP - One-in-four teenagers experiences at least one episode of depression before they reach the age of 18, a researcher said today. AAP News via NewsEdge Corporation : BRISBANE, July 14 AAP - One-in-four teenagers experiences at least one episode of depression before they reach the age of 18, a researcher said today. University of Queensland PhD student Gabrielle O'Shea, who is conducting an Australian-first depression treatment program for teenagers, said the ratio was consistent with other western countries. But depression overall was increasing in teenagers at a younger age than ever before. "There does seem to be a rise in the incidents of depression in teens," Ms O'Shea said. "By the time adolescents are 18-years-old, approximately 25 per cent of them will have experienced at least one episode of depression. "Individuals who have been born in the later part of the 20th century seem to be at greater risk for developing depression and it also seems to be manifesting at a younger age." Ms O'Shea said there was a number of contributing factors including relationship problems, genetics and the environment. She is using Interpersonal Therapy for Adolescents (IPT-A), which was designed to assist depressed teenagers overcome their symptoms. It was developed initially by researchers in the early 1980s in the United States and used more recently by a therapist at the Columbia University in New York. Ms O'Shea said it was the first time the therapy was used to treat depression in teens in Australia. She said finding effective psychological treatments were vital as opposed to prescribing medication. "Anti-depressant medications have relatively poor results with this group and if left untreated depression in adolescents is likely to occur," Ms O'Shea said. The University of Queensland is looking for teens to take part in 12-week treatment programs later in the year. People interested need to be 13-18 years of age and not taking any anti-depressant medication. AAP ved/sc/rsm/jlw Publication: AAP News Distributed by Financial Times Information Limited - Asia Africa Intelligence Wire <> << Copyright ©2003 Financial Times Limited, All Rights Reserved >> This site is best viewed with Internet Explorer 5.0
10 Июль, 2003
Эдгар По и Всеволод Гаршин: Одна болезнь, одна судьба - П. Бологов
07 Июль, 2003
Пополнение в разделе Пособия